I loved Red Dead Redemption, I think the underlying feeling of struggling against the encroachment of the modern world, and watching the end of the 'Wild West' was fantastic. I'd love to see them go in the opposite direction with the next one, so we could follow the story of the birth of the West, perhaps follow the great migration of Wagon Trails as people went in search of land to settle. I reckon there are a lot of great stories that could be created in that context.
The birth of the Wild West didn't necessarily take affect until the mid-late 1870's. That would be very interesting! Some people have suggested that it take place during the prohibition era (which would just make it another GTA, so it's probably a no-go). I think the next Red Dead should be the last one. What, really, is there more to say after the next one?
Yeah a prohibition era game would be too similar to GTA! I would love to see a prequel story about the life of Uncle and what led him to the state he is in at the time of Red Dead Redemption. I thought he was an interesting character for sure! There was a lot of questions about his story and how people treated him. But you're right, if they chose a new storyline, they'd soon run out of options to say any more!
I always got the impression that John Marston was too harsh on him! Maybe I need to replay it, it's been a couple years!
To be honest I'd prefer another Red Dead completely unrelated to Redemption. A fresh start.