The David Reimer/John Money case is really messed up. It get's brought up a lot in the context of discussing gender but you might want to read this about it: Source Also I recommended a book here if anyone is interested in learning about the construction of gender differences.In 2000, David and his twin brother (Brian) alleged that Dr. Money had taken numerous naked photos of the twins during their treatment and had forced them to engage in "sexual play" at age 7. In 2002, David's twin brother was found dead from an overdose of the drugs used to treat his schizophrenia. On 5 May 2004, shortly after being asked by his wife for a separation, Reimer committed suicide. Reimer's parents have stated that they believe Dr. Money's methodology was responsible for the deaths of both of their sons.