That's possible, though it really depends on what you want to do. I like C#, so I don't mind that side of it, but it's also a great resource for learning the visual languages as well. I guess it just depends on your programming tastes.

Yeah it's essentially a streamlined way to make a web app using ASP.net and (usually) Visual Studio. It separates the back end into Models, Views, and Controllers that all play their part in the development of a web app. It mainly uses HTML, CSS, Javascript, and C# and you can load JavaScript libraries and stuff with C# like ORMs. There's a lot of good info on the website: http://www.asp.net/mvc

Javascript and HTML5 can be really easy to learn if you just start doing simple web page projects. Just use Microsoft MVC and you'll be able to learn HTML, Javascript, CSS, and C# all in one package!