Spent 3 years in an AD lab and your slides are so much better than much of what I had to spend time not falling asleep to. (just reading the words PSEN1 is giving me flashbacks) Small critique: on slide 4, try and group the different aspects together with similar colors so it's more intuitive to look at. ie., plaques and tangles two different hues of green, so you can parse the two, but, without looking back and forth between the key an timeline, get a feel for how they relate to the pathological symptoms. You did that with neuronal loss and synaptic loss, and those are easier to remember than the others. I would put those next to each other in the key, and make LTP/LTD a "redder" more "danger" color like cognitive decline. (and help people understand just how wacky the animal models really are) Totally let us know when you've published, I'm a bit out-of-date in AD, but I still try to keep abreast of what's generally going on, and this seems very cool!
Psh, I put one of my labmates to sleep at the end of July. And that figure's hidden away in the appendix, but I updated another instance of LTP / LTD at your suggestion (and used non-acronym words since 2/3 of my committee are not neuroscientists). It's a bit late to update all the illustrator images of amyloid and tau though. And at the moment it's a fishing experiment with an interesting lead, unfortunately the follow-up cell work has been facing setbacks.