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comment by thundara
thundara  ·  3010 days ago  ·  link  ·    ·  parent  ·  post: Alzheimer's disease: Attack on amyloid-β protein

    My work (unrelated to AD) has recently had me focused on microglia, and the more I learn about them, the more I'm (1) fascinated and (2) dumbfounded.

Ditto, I'm looking at a group of host-recognition receptors on microglia. It's possible they turn down clearance of plaques. It's also possible they turn down clearance of synapses. The next two years will tell.