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- Everyone’s had the experience of leaving a conversation feeling frustrated, convinced the other person didn’t understand a word of what they were saying. Whether it’s a bad meeting with a coworker or an argument with a spouse, ineffective or negative communication may lead to more than just a bad day; new research has shown that it can change the neural pathways in our brains and foster long-lasting negativity. On the other hand, there’s evidence to suggest that positive words expressing values such as kindness and respect can go a long way toward building a better brain.