a thoughtful web.
Good ideas and conversation. No ads, no tracking.   Login or Take a Tour!
comment by thundara
thundara  ·  3580 days ago  ·  link  ·    ·  parent  ·  post: What science excites you?

I'm curious, have you read either of these papers? 1, 2

They seem pretty exciting and widely applicable!





Cumol  ·  3579 days ago  ·  link  ·  

Multiplex gene activation via CRISPR? This stuff is crazy!!!

thundara  ·  3579 days ago  ·  link  ·  

And repression, though I'm told by people In The Know that that's a tougher one to do well.

Pribnow  ·  3579 days ago  ·  link  ·  

I haven't seen either of those, but they're both really impressive. Now that we're pretty well able to splice genes into genomes, regulation of those spliced genes is becoming more and more important. There was a recent article I read about using XNA based genes in GMO plants so that in the absence of human-supplied nucleotides particular genes can't be reproduced, this brings to mind various methods of controlling not just the reproduction/lateral gene transfer, but the expression of the genes when it's most beneficial to the plants (or in particular tissues that need it the most and that we don't end up consuming).