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comment by kleinbl00
kleinbl00  ·  3698 days ago  ·  link  ·    ·  parent  ·  post: A very good writeup on ebola

FYI: I shared this article with my buddy Dr. Strangelove. He had this to say:

    One patient was received from the wild into a US hospital and treated "successfully" to completion. Now, after monitoring all of the potential patient contacts, only a single new case has emerged. While I write you one ear is on the news, expecting several more cases. But, the window for people to have become sick from exposure to Thomas Duncan is almost closed. Also, hopefully, we know that this nurse hasn't infected anyone else, because she was warned of the danger and was on watch for the infection.

    That said, there is a continued and growing risk that a mutant strain of Ebola virus might arise that can survive the measures that we currently think are adequate to contain it. If there were 5 or more cases now among the staff that treated Mr. Duncan, then I would be more concerned about that tham I am right now, tonight.




user-inactivated  ·  3698 days ago  ·  link  ·  

    That said, there is a continued and growing risk that a mutant strain of Ebola virus might arise that can survive the measures that we currently think are adequate to contain it.

I want to know the science here. I have a layman's grasp but really no way of telling for myself how real that risk is. I've read things that are all over the map. Some people claim ebola has already surely mutated at least somewhat just in the last few months, because we've allowed it continued contact to "learn" about humans for the longest period of time ever. That's the shit that makes me wonder.

kleinbl00  ·  3697 days ago  ·  link  ·  

    Although the australopithecines were far different from us, in the big scheme of things they lived not so long ago. Imagine going to a sporting event with sixty thousand seats around the stadium. You arrive early with your grandmother, and the two of you take the first seats. Next to your grandmother sits her grandmother, your great-great-grandmother. Next to her is your great-great-great-great-grandmother. The stadium fills with the ghosts of preceding grandmothers. An hour later the seat next to you is occupied by the last to sit down, the ancestor of you all. She nudges your elbow and you turn to find a strange nonhuman face. Beneath a low forehead and big brow-ridge, bright dark eyes surmount a massive jaw. Her long, muscular arms and short legs intimate her gymnastic climbing ability. She is your ancestor and a australopithecine, hardly a companion your grandmother can be expected to enjoy. She grabs an overhead beam and swings away over the crowd to steal some peanuts from a vendor.

    She is connected to you by over three million years of rain and sun and searching for food in the rich and scary African bush. Most australopithecines eventually went extinct but her lineage slowly changed. Evolutionarily, she was one of the lucky ones.

Richard Wrangham, Catching Fire: How Cooking Made Us Human

3 million years, 120,000 generations between you and a chimp. Fruit flies are a week between generations: 120,000 generations is 2300 years. Bacteria can be 10 hours: 120,000 generations is 130 years. Ebola? 8 hours.

The equivalent of "australopithecine" to "you" for the Ebola virus is 109 years. The first outbreak of Ebola Zaire was 38 years ago in 1976. On a human timescale, that was 1.6 million years ago, pretty much the endpoint of Homo Habilis:

There's a whole lot of evolution to be done when your life cycle lasts 8 hours. "3 months ago" to Ebola is 14,000 years ago to humans... and while we sure looked human, and we sure acted human, and we'd sure be recognizable as human, but 14,000 years ago, North America was probably devoid of human life.

TL;DR: Ebolution

user-inactivated  ·  3697 days ago  ·  link  ·  

You're, too, too right.

user-inactivated  ·  3697 days ago  ·  link  ·  

You're right.

It's strange that it hasn't changed since we encountered it in the '70s -- or has it? The lethality rate is way down from the halcyon 90 percent days, which could potentially work in the disease's advantage if it also learns to infect more efficiently. Maybe ... fuck.

b_b  ·  3697 days ago  ·  link  ·