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- The adaptations that allow bacteria, fungi and other pathogens to cause us harm can easily evolve outside the context of human disease. They are part of a microbial narrative that affects us, and can even kill us, but that isn’t about us.
I mean, we are talking about evolution here. It is literally just some guy hitting a "Randomize" button until they can get a somewhat round looking peg to fit into the round looking hole. Heck, sometimes it makes a small square peg that fits in the round hole. So long as it fits evolution doesn't give a shit. Everything about life is an accident, from bacteria beginning to attack humans to humans even existing in the first place. It just so happens things end up how they are, and at this point I'm sure that bacteria exist which have evolved in the human body to attack the human body, and I'm sure these were/are far more effective than the ones which evolved to live on a rock.