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The more helpless one feels when facing a given stressor, the more toxic that stressor’s effects. That sense of control tends to decline as one descends the socioeconomic ladder, with potentially grave consequences.
This is an interesting subject. There's a very nice National Geographic special called 'Stress: Portrait of a Killer' ( full shit here via YouTube ) that delves further into the whole animal study aspect of this. Baboons are nasty little fuckers.