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comment by mk
mk  ·  4582 days ago  ·  link  ·    ·  parent  ·  post: There’s more to your DNA than your DNA.
I came here to give Lamarck some props as well. It's incredible to think that my daughter was not only influenced by the genes I was given, but what I have been doing with them.

The stress thing is interesting. Have you noticed that centurions tend to have a very carefree view of things? I have to wonder if their longevity is in part due to a limited ability to experience epigenetically deleterious stress.





b_b  ·  4582 days ago  ·  link  ·  
Centenarians? Centurians were soldiers who commanded groups of 100.

But back to Lamarck. Don't give yourself too much credit :) Probably the wife has more to do with it than you. I think that you both could affect the methylation status of such and such gene, but that she probably has all the cards when it comes to regulatory RNAs and more of the share are transcription factors. Yet another reason to celebrate mothers...even if it is a day late.

mk  ·  4582 days ago  ·  link  ·  
    Centenarians? Centurians were soldiers who commanded groups of 100.

No, I was talking about awesome soldiers, and their positive outlook on life.

    But back to Lamarck. Don't give yourself too much credit :) Probably the wife has more to do with it than you. I think that you both could affect the methylation status of such and such gene, but that she probably has all the cards when it comes to regulatory RNAs and more of the share are transcription factors. Yet another reason to celebrate mothers...even if it is a day late.

You think? I would guess that the sperm factory is very susceptible to what is going on day to day, -maybe not regulatory RNAs so much, but who knows? Well, at least I chose the sex (meaning male or female).

b_b  ·  4582 days ago  ·  link  ·  
Well, the female has most of the cytoplasm. An very conservative approximation is the egg is a sphereoid of ~150um diameter and the sperm about 5um, a factor of 30, making the volumetric ratio a 900:1; or, there's a lot more shit in there to influence what happens.

    Well, at least I chose the sex (meaning male or female)

I hope that everyone just assumed this is what you meant, and you didn't have to qualify in the parentheses. If any of you didn't, then you should seek psychological help...immediately.