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comment by b_b
b_b  ·  3706 days ago  ·  link  ·    ·  parent  ·  post: The 2014 Chemistry Nobel: Beating the Diffraction LimitEmail This Entry

This is really cool work, and it's being deployed commercially now (albeit very expensively), but I can't quite figure out how it's the chemistry prize. Physics, perhaps. Or even medicine. Chemistry seems like a misplacement. As I understand the technology (as explained to me by a Nikon salesperson a few months ago--an extremely basic understanding, mind you), it a technique that uses many images and statistical modeling to back calculate where a fluorophore likely sits. Otherwise, it's standard fluorescence chemistry. The key is in getting ultra high speed laser scan acquisition, combined with advanced algorithms that model light scattering. Is it that they advanced the field of chemistry by coming up with this technology? Can't make heads or tails of it.





thundara  ·  3706 days ago  ·  link  ·  

I'd guess that last one, with an implicit "bio" tagged on the front, since I can't imagine traditional chemistry is massively into imaging their solutions...