Yeah. We'll just have to wait and see. Even so, if it's a 10% chance that the vaccine doesn't protect against this strain, that's a 10% chance of a global bummer. Global bummers ought to be like 0.01%. They don't call me depressing preprint guy for nothing. This one hot off the presses from Harvard and University of Pittsburg.Since coronaviruses have alower substitution rate than other RNA viruses this gave hope that spike glycoprotein is an antigenically stable vaccine target. However, we describe an evolutionary pattern of recurrent deletions at four antigenic sites in the spike glycoprotein. Deletions abolish binding of a reported neutralizing antibody. Circulating SARS-CoV-2 variants are continually exploring genetic and antigenic space via deletion in individual patients and at global scales. In viruses where substitutions are relatively infrequent, deletions represent a mechanism to drive rapid evolution, potentially promoting antigenic drift.