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Nah, the hardest thing is explaining why that's bad. "But we don't have to pay a systems administrator!" And if you really need the kind of scaling it's worth using a cloud service for, your application wants special care and feeding. But anyone you're having that discussion with has never met a good systems administrator, thinks of systems administrators as expensive janitors, and assumes the interesting problems a sysadmin should be solving belong to the application programmers instead.