Gluten is a well established pro-inflammatory molecule, and has effects in many people who don't even have celiac disease. Personally, I enjoy glutenous foods, because I love beer. But I could live without everything else fairly easily (says the dude who stuffs his face with cookies all day...I could stop, I swear). Systemic inflammation is a serious health hazard, and reducing foods from your diet that cause inflammation is probably a good way to reduce your long term risk of some diseases (and the corollary costs). I think that it's likely that a gluten free diet tends to reduce one's overall calorie intake, in addition to simply limiting gluten. Certainly there are calorie rich gluten free foods (e.g. potatoes, soda, candy bars), but kicking bread, beer, and pasta out of your diet will probably go a long way to cutting food consumption for most people. I imagine that for most people, going on a gluten-reduced diet, as opposed to a total avoidance, would probably be a wise move with respect to health.